ROUTERA


Chapter 12 Biotechnology and its Applications

Class 12th Biology Chapter Case Study


Case Study 1: Application of Biotechnology in Medicine

Biotechnology has revolutionized the field of medicine, particularly in the development of diagnostic tools, vaccines, and therapeutic agents. One major application is the production of recombinant proteins, such as human insulin and growth hormones, using genetically modified organisms (GMOs). Insulin was traditionally extracted from animals, but now it is produced in large quantities using E. coli bacteria that have been genetically modified to carry the human insulin gene. This advancement has improved the quality of life for people with diabetes and has made insulin more accessible and affordable worldwide.

Questions:

  1. Recombinant DNA technology is used in the production of:

    • A) Human insulin
    • B) Antibiotics
    • C) Enzymes for food processing
    • D) All of the above

    Answer: D) All of the above

  2. The gene for human insulin is inserted into E. coli bacteria using a:

    • A) Plasmid vector
    • B) Phage vector
    • C) Retrovirus
    • D) Liposome

    Answer: A) Plasmid vector

  3. Which of the following is the most important benefit of producing recombinant insulin through biotechnology?

    • A) It is cheaper and more accessible for patients
    • B) It can be produced in a wider variety of organisms
    • C) It is extracted directly from human cells
    • D) It has fewer side effects compared to animal-derived insulin

    Answer: A) It is cheaper and more accessible for patients

  4. The bacteria E. coli is commonly used in biotechnology because:

    • A) It is easy to culture and grow
    • B) It is a mammalian cell
    • C) It produces proteins with minimal modifications
    • D) It can only be used to produce human insulin

    Answer: A) It is easy to culture and grow


Case Study 2: Genetically Modified Crops and Food Production

Biotechnology has also made significant contributions to agriculture by developing genetically modified (GM) crops. One well-known example is Bt cotton, which has been genetically engineered to express a protein from Bacillus thuringiensis (Bt). This protein is toxic to certain pests like the bollworm, a major pest of cotton plants. Bt cotton reduces the need for chemical insecticides and helps increase cotton yields. Similarly, Golden Rice is a GM crop that has been engineered to produce beta-carotene, a precursor to vitamin A, addressing vitamin A deficiency in many developing countries.

Questions:

  1. Bt cotton is genetically modified to:

    • A) Produce more cotton fibers
    • B) Resist fungal infections
    • C) Produce a protein toxic to pests
    • D) Increase drought resistance

    Answer: C) Produce a protein toxic to pests

  2. Golden Rice is genetically engineered to:

    • A) Increase yield
    • B) Resist herbicides
    • C) Produce beta-carotene
    • D) Improve shelf life

    Answer: C) Produce beta-carotene

  3. The primary advantage of genetically modified crops like Bt cotton is:

    • A) Increased resistance to herbicides
    • B) Reduced dependence on chemical pesticides
    • C) Enhanced taste and texture
    • D) Increased nutritional value

    Answer: B) Reduced dependence on chemical pesticides

  4. A major concern regarding genetically modified crops is:

    • A) Loss of biodiversity
    • B) Increased cost of farming
    • C) Reduced growth rates of crops
    • D) High water usage

    Answer: A) Loss of biodiversity


Case Study 3: Enzyme Technology in Industry

In biotechnology, enzymes play a critical role in various industrial applications. One example is the use of amylase, an enzyme that breaks down starch into sugars, in the production of high-fructose corn syrup. Lipases are used in detergents, and proteases are used in the food industry for tenderizing meat. These enzymes are often produced by microorganisms like Aspergillus niger or Trichoderma reesei through fermentation processes. This biotechnological advancement has significantly reduced production costs and increased the efficiency of industrial processes.

Questions:

  1. The enzyme amylase is used in the production of:

    • A) High-fructose corn syrup
    • B) Proteins for pharmaceuticals
    • C) Insulin for diabetes treatment
    • D) Antibiotics

    Answer: A) High-fructose corn syrup

  2. The role of lipase in biotechnology is to:

    • A) Break down proteins in detergents
    • B) Convert starch into glucose
    • C) Catalyze the breakdown of fats
    • D) Produce antibiotics

    Answer: C) Catalyze the breakdown of fats

  3. Trichoderma reesei is a microorganism used to produce:

    • A) Amylase
    • B) Lipase
    • C) Protease
    • D) Cellulase

    Answer: D) Cellulase

  4. The use of enzymes in the detergent industry helps to:

    • A) Clean clothes faster
    • B) Remove stubborn stains and improve washing efficiency
    • C) Reduce energy consumption in washing machines
    • D) All of the above

    Answer: D) All of the above


Case Study 4: Bioremediation and Waste Management

Bioremediation is an eco-friendly technology that uses microorganisms to degrade environmental pollutants into less toxic substances. This process has been widely used to treat contaminated soil, water, and air. For example, the bacterium Pseudomonas putida is used to break down oil spills in marine environments. Bioremediation has also been applied in the treatment of heavy metal contamination, where certain microorganisms are capable of accumulating or transforming harmful metals into non-toxic forms.

Questions:

  1. Bioremediation involves the use of microorganisms to:

    • A) Clean up oil spills
    • B) Produce antibiotics
    • C) Synthesize food products
    • D) Increase agricultural productivity

    Answer: A) Clean up oil spills

  2. The bacterium Pseudomonas putida is used in:

    • A) Production of recombinant proteins
    • B) Treatment of oil spills
    • C) Genetic modification of crops
    • D) Fermentation processes

    Answer: B) Treatment of oil spills

  3. One of the primary advantages of bioremediation is:

    • A) It is a low-cost method of pollution management
    • B) It increases the nutrient content of polluted soil
    • C) It creates by-products that are harmful to the environment
    • D) It can be applied only to certain types of pollutants

    Answer: A) It is a low-cost method of pollution management

  4. Which of the following is a major limitation of bioremediation?

    • A) It cannot degrade all types of pollutants
    • B) It requires a lot of synthetic chemicals
    • C) It is time-consuming
    • D) It leads to the creation of harmful by-products

    Answer: A) It cannot degrade all types of pollutants


Case Study 5: Biotechnology in Forensic Science

Forensic biotechnology plays a vital role in criminal investigations through DNA fingerprinting. DNA profiling uses specific regions of the DNA that vary greatly between individuals to identify individuals based on their unique genetic markers. This technology has been crucial in solving crimes, paternity testing, and identifying victims of natural disasters. Forensic scientists use short tandem repeats (STRs) in DNA for matching crime scene evidence to suspects.

Questions:

  1. DNA fingerprinting is used in:

    • A) Identifying individuals in criminal investigations
    • B) Producing recombinant proteins
    • C) Growing genetically modified crops
    • D) Producing vaccines

    Answer: A) Identifying individuals in criminal investigations

  2. The technique of DNA profiling involves the analysis of:

    • A) Short tandem repeats (STRs)
    • B) The entire genome of an individual
    • C) The protein coding regions of the DNA
    • D) Mitochondrial DNA only

    Answer: A) Short tandem repeats (STRs)

  3. DNA fingerprinting is useful in:

    • A) Paternity testing
    • B) Identifying unknown crime scene evidence
    • C) Solving cold cases
    • D) All of the above

    Answer: D) All of the above

  4. The major advantage of DNA profiling over other forensic techniques is:

    • A) It can be used for identifying unknown substances
    • B) It allows for the analysis of biological materials such as blood and hair
    • C) It does not require any prior knowledge of the suspect
    • D) It is a quicker process

    Answer: B) It allows for the analysis of biological materials such as blood and hair